Glycosylated hemoglobin levels and lipid profile in children with asthma using low dose and high dose inhaled corticosteroids

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Hemoglobin a1c levels in children with asthma using low dose inhaled corticosteroids.

OBJECTIVES Steroids may raise the blood glucose levels as a systemic effect. Due to this, the potential effect of prophylactic use of inhaled steroids (ICS) on HbA1c levels in children with asthma was investigated. STUDY DESIGN Case control study. ? SETTING Outpatient department. PARTICIPANTS 141 children with asthma but without diabetes (study group) and 52 children without diabetes or a...

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Adrenal function and high dose inhaled corticosteroids for asthma.

OBJECTIVE To investigate effects on adrenal function of fluticasone, a recently released inhaled steroid preparation with lower systemic bioavailability than beclomethasone dipropionate. METHODS 34 children on high doses (400-909 micrograms/m2/d) of inhaled beclomethasone dipropionate or budesonide were recruited into a double blind, crossover study investigating the effects on adrenal functi...

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Comparison of high dose inhaled steroids, low dose inhaled steroids plus low dose theophylline, and low dose inhaled steroids alone in chronic asthma in general practice.

BACKGROUND Theophylline is widely used in the treatment of asthma, and there is evidence that theophylline has anti-inflammatory or immunomodulatory effects. A study was undertaken to determine whether theophylline added to low dose inhaled steroids would be as efficacious as high dose inhaled steroids in asthma. METHODS In a study in general practice of 155 recruited asthmatic patients with ...

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Absorption of high-dose inhaled corticosteroids.

The appropriate and safe use of inhaled corticosteroids (ICS) is an important issue in managing asthma, and we read with interest the article by Wales et al (June 1999).1 This is now the seventh report showing increased adrenal suppression with very high doses of fluticasone propionate (FP) compared to budesonide (BUD) in volunteers.2–7 However, normal subjects do not generally receive these do...

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Purpura and dermal thinning associated with high dose inhaled corticosteroids.

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ژورنال

عنوان ژورنال: Indian Journal of Allergy, Asthma and Immunology

سال: 2015

ISSN: 0972-6691

DOI: 10.4103/0972-6691.162977